Non-sedating oral antihistamines

Non-sedating oral antihistamines

Sedating antihistamines cause sedation as they are highly lipid soluble and readily cross the blood brain barrier. This sedating activity is sometimes used in managing conditions such as eczema where sleep maybe disturbed due to pruritus. Sedating antihistamines also have significant antimuscarinic activity and should be used with caution in patients with prostatic hypertrophy, urinary retention and angle-closure glaucoma.

Sedating Antihistamines and Non-Sedating Antihistamines

Antihistamines non-sedating

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    The non-sedating antihistamines include cetirizine, desloratadine, fexofenadine, levocetirizine and loratadine.